Huashan Zhang
Hubei University of Technology, China
Title: Angiotensin I-converting enzyme inhibitory activity in a hydrolysate of mycelia proteins from Monascus rubber
Biography
Biography: Huashan Zhang
Abstract
Inhibitory peptides of Angiotensin I-converting enzyme (ACE) were to be isolated from the hydrolysates of the mycelia of Monascus rubber. Three enzymatic methods were compared and found the most effective hydrolysate method for ACE inhibition was multi-level composite enzymes including alkaline protease, flavourzyme and pepsin. Fractions E-3, the most effective fractions which shown to exhibit ACE inhibitory activity with IC50 values of 0.063mg/mL. The results indicate that the hydrolysates of Monascus mycelia from Monascus rubber are potential leads for the development of functional foods or pharmaceuticals against hypertension.